@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<https://www.ehealth.fgov.be/standards/fhir/registries/bcr/CodeSystem/bcr-molecular-marker> a fhir:CodeSystem ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "bcr-molecular-marker"] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div [ fhir:v "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem bcr-molecular-marker</b></p><a name=\"bcr-molecular-marker\"> </a><a name=\"hcbcr-molecular-marker\"> </a><p>This case-sensitive code system <code>https://www.ehealth.fgov.be/standards/fhir/registries/bcr/CodeSystem/bcr-molecular-marker</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">ER<a name=\"bcr-molecular-marker-ER\"> </a></td><td>Estrogen receptor</td><td>Oestrogeen receptor status (ER).</td></tr><tr><td style=\"white-space:nowrap\">PR<a name=\"bcr-molecular-marker-PR\"> </a></td><td>Progesterone receptor</td><td>Progesteron receptor status (PR).</td></tr><tr><td style=\"white-space:nowrap\">HER2-IHC<a name=\"bcr-molecular-marker-HER2-IHC\"> </a></td><td>HER2 IHC score</td><td>HER2 IHC score (0 / 1+ / 2+ / 3+).</td></tr><tr><td style=\"white-space:nowrap\">HER2-IHC-ISH<a name=\"bcr-molecular-marker-HER2-IHC-ISH\"> </a></td><td>HER2 status (IHC + ISH combined)</td><td>HER2 status op basis van IHC en ISH.</td></tr><tr><td style=\"white-space:nowrap\">BRCA1-2<a name=\"bcr-molecular-marker-BRCA1-2\"> </a></td><td>BRCA1/2</td><td>BRCA1/2 mutation status.</td></tr><tr><td style=\"white-space:nowrap\">CHEK2<a name=\"bcr-molecular-marker-CHEK2\"> </a></td><td>CHEK2</td><td>CHEK2 mutation status. Spelled 'CHECK2' on the source form.</td></tr><tr><td style=\"white-space:nowrap\">PALB2<a name=\"bcr-molecular-marker-PALB2\"> </a></td><td>PALB2</td><td>PALB2 mutation status.</td></tr><tr><td style=\"white-space:nowrap\">ATM<a name=\"bcr-molecular-marker-ATM\"> </a></td><td>ATM</td><td>ATM mutation status.</td></tr><tr><td style=\"white-space:nowrap\">PIK3CA<a name=\"bcr-molecular-marker-PIK3CA\"> </a></td><td>PIK3CA</td><td>PIK3CA mutation status. Spelled 'PIKCA3' on the source form.</td></tr><tr><td style=\"white-space:nowrap\">KI67<a name=\"bcr-molecular-marker-KI67\"> </a></td><td>Ki-67 before systemic therapy</td><td>Ki-67 vóór systemische therapie. Result is expressed as a percentage.</td></tr><tr><td style=\"white-space:nowrap\">OTHER<a name=\"bcr-molecular-marker-OTHER\"> </a></td><td>Other</td><td>Other marker — free-text marker name expected.</td></tr></table></div>"^^rdf:XMLLiteral ]
  ] ; # 
  fhir:url [
     fhir:v "https://www.ehealth.fgov.be/standards/fhir/registries/bcr/CodeSystem/bcr-molecular-marker"^^xsd:anyURI ;
     fhir:l <https://www.ehealth.fgov.be/standards/fhir/registries/bcr/CodeSystem/bcr-molecular-marker>
  ] ; # 
  fhir:version [ fhir:v "0.1.0"] ; # 
  fhir:name [ fhir:v "BCRMolecularMarker"] ; # 
  fhir:title [ fhir:v "BCR Molecular Marker"] ; # 
  fhir:status [ fhir:v "draft"] ; # 
  fhir:experimental [ fhir:v true] ; # 
  fhir:date [ fhir:v "2026-05-04T06:30:16+00:00"^^xsd:dateTime] ; # 
  fhir:publisher [ fhir:v "eHealth Platform Belgium"] ; # 
  fhir:contact ( [
     fhir:name [ fhir:v "eHealth Platform Belgium" ] ;
     fhir:telecom ( [
       fhir:system [ fhir:v "url" ] ;
       fhir:value [ fhir:v "https://www.ehealth.fgov.be" ]
     ] [
       fhir:system [ fhir:v "email" ] ;
       fhir:value [ fhir:v "info@ehealth.fgov.be" ]
     ] )
  ] ) ; # 
  fhir:description [ fhir:v "Molecular markers listed on Bijlage 55 vervolg 1. The form spells PIK3CA as 'PIKCA3'; the canonical gene symbol is preserved here."] ; # 
  fhir:jurisdiction ( [
     fhir:coding ( [
       fhir:system [
         fhir:v "urn:iso:std:iso:3166"^^xsd:anyURI ;
         fhir:l <urn:iso:std:iso:3166>
       ] ;
       fhir:code [ fhir:v "BE" ] ;
       fhir:display [ fhir:v "Belgium" ]
     ] )
  ] ) ; # 
  fhir:caseSensitive [ fhir:v true] ; # 
  fhir:content [ fhir:v "complete"] ; # 
  fhir:count [ fhir:v "11"^^xsd:nonNegativeInteger] ; # 
  fhir:concept ( [
     fhir:code [ fhir:v "ER" ] ;
     fhir:display [ fhir:v "Estrogen receptor" ] ;
     fhir:definition [ fhir:v "Oestrogeen receptor status (ER)." ]
  ] [
     fhir:code [ fhir:v "PR" ] ;
     fhir:display [ fhir:v "Progesterone receptor" ] ;
     fhir:definition [ fhir:v "Progesteron receptor status (PR)." ]
  ] [
     fhir:code [ fhir:v "HER2-IHC" ] ;
     fhir:display [ fhir:v "HER2 IHC score" ] ;
     fhir:definition [ fhir:v "HER2 IHC score (0 / 1+ / 2+ / 3+)." ]
  ] [
     fhir:code [ fhir:v "HER2-IHC-ISH" ] ;
     fhir:display [ fhir:v "HER2 status (IHC + ISH combined)" ] ;
     fhir:definition [ fhir:v "HER2 status op basis van IHC en ISH." ]
  ] [
     fhir:code [ fhir:v "BRCA1-2" ] ;
     fhir:display [ fhir:v "BRCA1/2" ] ;
     fhir:definition [ fhir:v "BRCA1/2 mutation status." ]
  ] [
     fhir:code [ fhir:v "CHEK2" ] ;
     fhir:display [ fhir:v "CHEK2" ] ;
     fhir:definition [ fhir:v "CHEK2 mutation status. Spelled 'CHECK2' on the source form." ]
  ] [
     fhir:code [ fhir:v "PALB2" ] ;
     fhir:display [ fhir:v "PALB2" ] ;
     fhir:definition [ fhir:v "PALB2 mutation status." ]
  ] [
     fhir:code [ fhir:v "ATM" ] ;
     fhir:display [ fhir:v "ATM" ] ;
     fhir:definition [ fhir:v "ATM mutation status." ]
  ] [
     fhir:code [ fhir:v "PIK3CA" ] ;
     fhir:display [ fhir:v "PIK3CA" ] ;
     fhir:definition [ fhir:v "PIK3CA mutation status. Spelled 'PIKCA3' on the source form." ]
  ] [
     fhir:code [ fhir:v "KI67" ] ;
     fhir:display [ fhir:v "Ki-67 before systemic therapy" ] ;
     fhir:definition [ fhir:v "Ki-67 vóór systemische therapie. Result is expressed as a percentage." ]
  ] [
     fhir:code [ fhir:v "OTHER" ] ;
     fhir:display [ fhir:v "Other" ] ;
     fhir:definition [ fhir:v "Other marker — free-text marker name expected." ]
  ] ) . # 

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