{
  "resourceType" : "CodeSystem",
  "id" : "bcr-molecular-marker",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem bcr-molecular-marker</b></p><a name=\"bcr-molecular-marker\"> </a><a name=\"hcbcr-molecular-marker\"> </a><p>This case-sensitive code system <code>https://www.ehealth.fgov.be/standards/fhir/registries/bcr/CodeSystem/bcr-molecular-marker</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">ER<a name=\"bcr-molecular-marker-ER\"> </a></td><td>Estrogen receptor</td><td>Oestrogeen receptor status (ER).</td></tr><tr><td style=\"white-space:nowrap\">PR<a name=\"bcr-molecular-marker-PR\"> </a></td><td>Progesterone receptor</td><td>Progesteron receptor status (PR).</td></tr><tr><td style=\"white-space:nowrap\">HER2-IHC<a name=\"bcr-molecular-marker-HER2-IHC\"> </a></td><td>HER2 IHC score</td><td>HER2 IHC score (0 / 1+ / 2+ / 3+).</td></tr><tr><td style=\"white-space:nowrap\">HER2-IHC-ISH<a name=\"bcr-molecular-marker-HER2-IHC-ISH\"> </a></td><td>HER2 status (IHC + ISH combined)</td><td>HER2 status op basis van IHC en ISH.</td></tr><tr><td style=\"white-space:nowrap\">BRCA1-2<a name=\"bcr-molecular-marker-BRCA1-2\"> </a></td><td>BRCA1/2</td><td>BRCA1/2 mutation status.</td></tr><tr><td style=\"white-space:nowrap\">CHEK2<a name=\"bcr-molecular-marker-CHEK2\"> </a></td><td>CHEK2</td><td>CHEK2 mutation status. Spelled 'CHECK2' on the source form.</td></tr><tr><td style=\"white-space:nowrap\">PALB2<a name=\"bcr-molecular-marker-PALB2\"> </a></td><td>PALB2</td><td>PALB2 mutation status.</td></tr><tr><td style=\"white-space:nowrap\">ATM<a name=\"bcr-molecular-marker-ATM\"> </a></td><td>ATM</td><td>ATM mutation status.</td></tr><tr><td style=\"white-space:nowrap\">PIK3CA<a name=\"bcr-molecular-marker-PIK3CA\"> </a></td><td>PIK3CA</td><td>PIK3CA mutation status. Spelled 'PIKCA3' on the source form.</td></tr><tr><td style=\"white-space:nowrap\">KI67<a name=\"bcr-molecular-marker-KI67\"> </a></td><td>Ki-67 before systemic therapy</td><td>Ki-67 vóór systemische therapie. Result is expressed as a percentage.</td></tr><tr><td style=\"white-space:nowrap\">OTHER<a name=\"bcr-molecular-marker-OTHER\"> </a></td><td>Other</td><td>Other marker — free-text marker name expected.</td></tr></table></div>"
  },
  "url" : "https://www.ehealth.fgov.be/standards/fhir/registries/bcr/CodeSystem/bcr-molecular-marker",
  "version" : "0.1.0",
  "name" : "BCRMolecularMarker",
  "title" : "BCR Molecular Marker",
  "status" : "draft",
  "experimental" : true,
  "date" : "2026-05-04T06:30:16+00:00",
  "publisher" : "eHealth Platform Belgium",
  "contact" : [{
    "name" : "eHealth Platform Belgium",
    "telecom" : [{
      "system" : "url",
      "value" : "https://www.ehealth.fgov.be"
    },
    {
      "system" : "email",
      "value" : "info@ehealth.fgov.be"
    }]
  }],
  "description" : "Molecular markers listed on Bijlage 55 vervolg 1. The form spells PIK3CA as 'PIKCA3'; the canonical gene symbol is preserved here.",
  "jurisdiction" : [{
    "coding" : [{
      "system" : "urn:iso:std:iso:3166",
      "code" : "BE",
      "display" : "Belgium"
    }]
  }],
  "caseSensitive" : true,
  "content" : "complete",
  "count" : 11,
  "concept" : [{
    "code" : "ER",
    "display" : "Estrogen receptor",
    "definition" : "Oestrogeen receptor status (ER)."
  },
  {
    "code" : "PR",
    "display" : "Progesterone receptor",
    "definition" : "Progesteron receptor status (PR)."
  },
  {
    "code" : "HER2-IHC",
    "display" : "HER2 IHC score",
    "definition" : "HER2 IHC score (0 / 1+ / 2+ / 3+)."
  },
  {
    "code" : "HER2-IHC-ISH",
    "display" : "HER2 status (IHC + ISH combined)",
    "definition" : "HER2 status op basis van IHC en ISH."
  },
  {
    "code" : "BRCA1-2",
    "display" : "BRCA1/2",
    "definition" : "BRCA1/2 mutation status."
  },
  {
    "code" : "CHEK2",
    "display" : "CHEK2",
    "definition" : "CHEK2 mutation status. Spelled 'CHECK2' on the source form."
  },
  {
    "code" : "PALB2",
    "display" : "PALB2",
    "definition" : "PALB2 mutation status."
  },
  {
    "code" : "ATM",
    "display" : "ATM",
    "definition" : "ATM mutation status."
  },
  {
    "code" : "PIK3CA",
    "display" : "PIK3CA",
    "definition" : "PIK3CA mutation status. Spelled 'PIKCA3' on the source form."
  },
  {
    "code" : "KI67",
    "display" : "Ki-67 before systemic therapy",
    "definition" : "Ki-67 vóór systemische therapie. Result is expressed as a percentage."
  },
  {
    "code" : "OTHER",
    "display" : "Other",
    "definition" : "Other marker — free-text marker name expected."
  }]
}